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News
More data, more answers? A 1.9 million-person health study shows why scale has limits
5+ hour, 28+ min ago (584+ words) One of the world's largest health cohorts provides researchers with an unusually detailed view of disease across Britain, but comparisons with national surveys and established biobanks reveal that sample size is only part of the picture. Study: Phenomic profiles and…...
APOE genotype helps p-tau217 predict who may develop cognitive impairment sooner
6+ hour, 5+ min ago (751+ words) A pooled analysis across seven multiethnic cohorts examines whether the same p-tau217 reading carries the same prognostic meaning for people with different APOE backgrounds. Study: Plasma phosphorylated tau 217 concentrations, APOE genotype, and timing of cognitive impairment in individuals across diverse racial…...
A study of ayahuasca users found a mental health pattern researchers cannot yet explain
6+ hour, 33+ min ago (705+ words) Researchers compared first-time and experienced ayahuasca users to see how prior exposure relates to mood, stress, spirituality, substance use, and beliefs about consciousness. Close-up of Banisteriopsis Caapi vines, one of the Ayahuasca plants. Study: Prior ayahuasca experience is associated with…...
A large US study found no overall link between fluoride in pregnancy and children’s behavior
7+ hour, 25+ min ago (716+ words) Researchers tracked prenatal exposure to public-water fluoride across 34 US states to examine whether concentrations during pregnancy were associated with children’s later emotional and behavioral health. A recent study published in the journal JAMA Network Open found that prenatal exposure to…...
Healthy ageing shaped by more varied biology than previously thought
1+ week, 4+ day ago (410+ words) Molecular changes of ageing are far more unique than previously thought, meaning two healthy individuals of identical age can experience significantly different ageing journeys. A new study, led by researchers at King’s College London and the most comprehensive molecular study…...
Distinct EFEMP1 variants cause different forms of vision loss
2+ day, 10+ hour ago (248+ words) No name has been formally given for the newly discovered condition, but the researchers are referring to it as EFEMP1-associated late-onset retinal degeneration (L-ORD). It occurs due to the p.Arg140Trp variant in the EFEMP1 gene, which causes abnormally thick material to build…...
FDA clears trial of dual-targeted CAR T-cell therapy for cancer
2+ day, 10+ hour ago (778+ words) The U.S. Food and Drug Administration this week granted permission for investigators at the University of Colorado Anschutz to conduct a clinical trial testing genetically engineered immune cells in adults with advanced colorectal cancer and pediatric patients with solid cancers who…...
Targeted nanoparticles strengthen anti-cancer immune responses in tumors
2+ day, 10+ hour ago (165+ words) Adelaide University researchers have developed a new way of using mRNA technology to reprogram tumor-supporting immune cells and strengthen the body's anti-cancer immune response. Targeted nanoparticles strengthen anti-cancer immune responses in tumors Adelaide University researchers have developed a new way…...
Obesity suppresses natural protection against breast cancer growth
2+ day, 10+ hour ago (256+ words) Breasts are mostly composed of fat, particularly fat cells called adipocytes. These adipocytes are different depending on a person's weight and can be lean or obese. In obesity, adipocytes are larger than in their lean counterparts. Hilgendorf also says that…...
AI identifies hidden biological patterns to accurately diagnose migraines
2+ day, 22+ hour ago (973+ words) AI can trawl vast amounts of health data which is not specifically related to migraines, but which can be used to identify people predisposed to the condition. A new study from NTNU - the Norwegian University of Science and Technology - reveals…...