7+ hour, 11+ min ago   (117+ words) PharmaDispatch Noxopharm moves lupus skin therapy toward next human trial Noxopharm announced that its lead experimental therapy, SOF-SKN, will advance to an extension clinical study in patients with cutaneous lupus erythematosus, a painful, disfiguring skin condition for which no targeted…...

9+ hour, 34+ min ago   (539+ words) A reflection of my time researching physical activity and Parkinson’s disease Exercise is routinely recommended to people with Parkinson’s disease. The …...

19+ hour, 15+ min ago   (239+ words) The key findings of the study were: • Postoperatively, 10 patients (14.3%) showed lateral knee skin swelling with perfusion impairment. • The distance from the center of the perfusion-compromised area to the joint line was 1.9 ± 0.6 cm, and the area of perfusion deficit was 15.0 ± 6.6 cm2; all…...

1+ day, 1+ hour ago   (431+ words) Photodynamic therapy, or PDT, has long been regarded as a precisely local cancer treatment: a photosensitizing drug is delivered to a tumor, light of a specific wavelength activates it, and the resulting reactive oxygen species destroy the illuminated cells....

1+ day, 6+ hour ago   (746+ words) A new commentary published in the Journal of Cancer Research and Clinical Oncology is challenging how exceptional individual responses to an experimental multiple myeloma drug should be interpreted, warning that remarkable case reports can inadvertently obscure evidence that a treatment…...

1+ day, 11+ hour ago   (55+ words) Intracerebral hemorrhage is the deadliest and most disabling form of stroke, yet some of its cruelest consequences unfold quietly, months or even years after the initial bleed. Survivors frequently develop depression, anxiety, apathy, cognitive impairment, fatigue, and disrupted sleep, symptoms…...

1+ day, 14+ hour ago   (646+ words) A groundbreaking international consensus effort has, for the first time, established detailed expert guidance on how to safely deliver CPX-351, a liposomal formulation of cytarabine and daunorubicin, to patients with therapy-related acute myeloid leukaemia (t-AML) and acute myeloid leukaemia with…...

2+ day, 4+ hour ago   (1349+ words) {“title”:”AI-Enabled Clinical Trials Are Poised to Transform How New Medicines Are Tested”,”html”:”Clinical trials have long been the slowest, most expensive and most unpredictable stage of medical research. A promising molecule identified in the laboratory can take a…...

3+ day, 5+ hour ago   (424+ words) Etcamah is a once-daily pill that breaks down the estrogen receptor many breast cancers use to grow and is already approved for a narrower group of breast cancer patients. The setback lands on a pipeline already under scrutiny. Shares of…...

2+ day, 20+ hour ago   (541+ words) Clinical trials let researchers test new drugs, medical devices, and interventions to improve outcomes across many diseases. But in order for these studies to deliver the most impactful results, they need to include participants from different racial and ethnic backgrounds....